Monoclonal Antibodies & Oral Antivirals

Updated: January 18, 2022

The COVID-19 vaccine offers the best defense against the virus that causes COVID-19. For info on the COVID-19 vaccine, text your ZIP code to 438829.

There is currently no cure for COVID-19. The most effective way to prevent COVID-19 is by getting vaccinated. If you or a loved one contracts COVID-19, there are a few therapies that may be effective in treating symptoms from COVID-19. These therapies should not be considered an alternative to vaccination.

ALERT - Monoclonal Antibody Therapy and Oral Antiviral Medications have received emergency use authorization (EUA) for the treatment of COVID-19 symptoms. However, supplies are limited; prescriptions for therapies/medications will be available on a first-come, first-served basis for those who meet medical criteria.

Don't Wait - talk to your Doctor

Monoclonal Antibody Therapy

Monoclonal antibodies are laboratory-made proteins that mimic the immune system’s ability to fight off harmful pathogens such as viruses. Several new therapies are specifically directed against the spike protein of SARS-CoV-2, helping protect patients from COVID-19 illness.

Two national resources list medical offices that may provide monoclonal antibodies:

Studies show this medicine may be a promising treatment for COVID-19 symptoms in certain high-risk individuals when taken within a certain window of time. It may help people who:

  • Have a positive COVID-19 viral test; AND
  • Are symptomatic with mild to moderate COVID-19 for 10 days or less; AND
  • Are at high risk of progressing to severe COVID-19 and/or hospitalization.

This therapy is available for eligible patients from limited health care providers in Inyo County.  We encourage patients to talk with their doctor about this option and whether it’s a good match for your situation. The Public Health Department is helping approved health care providers get the antibody therapies to be administered by IV infusion.

The Patient’s Physician should call ahead to see if the approved health care providers currently have supply of the monoclonal antibodies, that there are available appointments, and to confirm they (the patient) meet criteria to receive the therapy treatment.

If you are experiencing symptoms of severe disease should seek care right away
Sotrovimab

Note: This therapy is available in Inyo County for eligible patients, supplies are limited.

Sotovimab is a monoclonal antibody to be administered together for the treatment of mild to moderate COVID-19 symptoms in patients 12 years of age or older. Sotovimab is a monoclonal antibody that is specifically directed against the spike protein of SARS-CoV-2 and is designed to block the virus’ attachment and entry into human cells.

 

Regeneron

Note: This therapy is available in Inyo County for eligible patients, supplies are limited.

Regeneron is a combination of casirivimab and imdevimab to be administered together for the treatment of mild to moderate COVID-19 symptoms in patients 12 years of age or older. Casirivimab and imdevimab are monoclonal antibodies that are specifically directed against the spoke protein of SARS-CoV-2, designed to block the virus’ attachment and entry into human cells.

 

Eli Lilly

Note: This therapy is available in Inyo County for eligible patients, supplies are limited.

Eli Lilly is a combination of Bamlanivimab and Etesevimab. Both are monoclonal antibodies to be administered together and may be used as post-exposure prophylaxis for adults and pediatric patients.

Update: Bamlanivimab and etesevimab have also received EUA authorization for those ages 0-11 (i.e. allowing for treatment of eligible newborns) in addition to ages 12+.

 

EVUSHELD

Note: This therapy is not available in Inyo County.

 

Oral Antiviral Pills

If you have tested positive for COVID-19 and are at risk for developing severe symptoms due to your age or underlying health conditions, talk to your doctor about if oral antiviral pills may be right for you.

Paxlovid

Note: This medication is available in Inyo County for eligible patients at Dwayne's Friendly Pharmacy, a prioritization criteria form is required with each prescription; supplies are limited.

Paxlovidis a take-at-home course of pills that does not prevent disease like vaccines do, but preliminary data shows it may reduce the risk of hospitalization and death by about 88% when the pills are started within five days of becoming sick, for patients at high risk of severe illness.

These pills may be a promising treatment for COVID-19 symptoms in people who are at highest risk for severe illness and death. It may help people who:

  • Have a positive SARS-CoV-2 (COVID-19) viral test; AND
  • Are symptomatic with mild to moderate COVID-19; AND
  • Are at high risk of progressing to severe COVID-19 and/or hospitalization.

 

Molnupiravir

Note: This medication is available in Inyo County for eligible patients at Dwayne's Friendly Pharmacy, a prioritization criteria form is required with each prescription; supplies are limited.

Molnupiravir is a set of take-at-home pills that does not prevent disease like vaccines do, but may reduce the risk of severe illness (requiring hospitalization) and death by about 30% when the pills are started within five days of becoming sick. It has received emergency use authorization for people at high risk for severe illness for whom alternative COVID-19 medication options authorized by the FDA are not accessible or clinically appropriate.

These pills may be a promising treatment for COVID-19 symptoms in people who are at highest risk for severe illness and death. It may help people who:

  • Have a positive SARS-CoV-2 (COVID-19) viral test; AND
  • Are symptomatic with mild to moderate COVID-19; AND
  • Are at high risk of progressing to severe COVID-19 and/or hospitalization.
  • The use of Molnupiraviris not recommended during pregnancy.

 

Several medications, including ivermectin and hydroxychloroquine, have been touted online as potential treatments for COVID-19, but these medications have not been proven effective in treating COVID-19. Providers cannot prescribe medications for the treatment of COVID-19 that have not been approved for that purpose.

 

Note for Inyo County Health Care Providers: 

The federal government will be allocating Paxlovid & Molnupiravir to states, and the California Department of Public Health (CDPH) will allocate Paxlovid/Molnupiravir to local health jurisdictions based on new COVID-19 cases and an equity measure. Given the limited amount of Paxlovid & Molnupiravir available, product scarcity is expected.

Prioritization Criteria Forms are required to fill any prescription for Paxlovid or Molnupiravir. If you need the most recent copy of the form or have questions, please contact Public Health via email: healthofficer@inyocounty.us 

 

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